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Objective:To explore the research focus, frontier and trend of global reseaches about low back pain using bibliometrics and visualization technology. Methods:The researchs in the Web of Science core database from 2016 to 2020 were retrieved with the subject terms of "low back pain" and categories of rehabilitation, and analyzed with Creating Citation Reports and Analyzing Retrieval Results of Web of Science, as well as the CiteSpace. Results:A total of 2026 papers were retrieved. The total frequency of citations in the last five years was 6793. The number of papers and citations increased year by year. Most of the papers came from the countries of America, Europe and Australia; the top five university institutions also with high centrality; and funded by US National Research Fund mostly. The top ten journals for number of papers and cited frequency were mainly rehabilitation journals, and the researches mainly focused on orthopedics, sports medicine and healthcare medicine. A total of 468 key words were obtained, including 33 key words with high centrality and 29 key words with Strongest Citation Bursts. Nine papers of highly cited were suggested by Web of Science. A total of 466 references were obtained through CiteSpace, including 35 references with high centrality and 53 references with Strongest Citation Bursts. The researches of key node literature were mainly randomized controlled trails and systematic review. Conclusion:The researches of low back pain mainly focus on the mechanism and management of pain, such as central sensitization, pressure pain threshold, pain pattern classification, pain directional preference and centralization, pain physiology/neuroscience education, and nonpharmacologic strategies for comprehensive pain care; as well as the psychological and social factors, such as behavioral cognitive therapy/psychologically informed physical therapy, self-efficacy, kinesiophobia, fear avoidance, and variables and interventions related to return-to-work. The trial studies of STarT Back tool, core instruments and standardization of core outcome reporting in clinical trials, and individualized and targeted treatment, would be the global trends in the research of low back pain.
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BACKGROUND: Regeneration and repair using platelet-rich plasma provide a new insight for treating tendinopathy, which exhibits good outcomes in the treatment of refractory tendon and ligament degenerative diseases. OBJECTIVE: To explore the current research hotspot in the treatment of tendinopathy with platelet-rich plasma worldwide through drawing the scientific knowledge map of the treatment to tendinopathy by using the information visualization tool. METHODS: Using citation analysis method, we searched Web of Science core database for the studies on platelet-rich plasma and tendinopathy since 2008. The scientometric and visual analyses of literature were carried out by using Cite Space V scientific knowledge map tool. RESULTS AND CONCLUSION: (1) A total of 515 papers on repair of tendinitis with platelet-rich plasma were recruited. Eight papers on key nodes were obtained, and 27 keywords were found at high frequency. (2) In recent decade, high-yield authors have formed a research group based on the state and research institutions. The inter group cooperation is close, but there is a lack of cross-group scientific research cooperation. (3) Platelet-rich plasma has been widely used in the clinical treatment of tendinopathy, but there are some shortcomings in the design of clinical practice and experimental research, leading to controversy about the therapeutic effect of platelet-rich plasma. In order to evaluate the efficacy of platelet-rich plasma in tendinopathy, basic experimental studies should be carried out on the premise of controlling the experimental conditions and overcoming the shortcomings in experimental design. (4) The research of platelet-rich plasma on tendinopathy in foreign countries has gradually developed from the initial clinical study of platelet-rich plasma on the treatment of tendinopathy to the in vitro experiment with time, which has become a hotspot. In the selection of experimental indicators, the functional study of cytokines contained in platelet-rich plasma has shifted to focus on gene expression in cell biology. It is still unclear which cell transduction pathways platelet-rich plasma can affect tendon healing. From the trend of research, future research in this field will focus on microbiological mechanism of platelet-rich plasma in tendinopathy treatment.
ABSTRACT
The paper takes literature in the Health Technology Assessment (HTA) field in Web of Science and " China Academic Journal Network Publishing Database" as its study subject,draws scientific knowledge map with EXCEL,CiteSpace on data like high-frequency keywords and burst terms and analyzes study hotspots and evolution trend.It suggests that HTA theoretical system be perfected,study be converted into demonstration and study cooperation be strengthened to promote study and development of China's HTA.